GLB1 Antibody

ProSci
Product Code: PSI-59-277
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-277-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A549 cell line lysates (35ug/lane).

Western blot analysis in A549 cell line lysates (35ug/lane).

Further Information

Additional Names:
Beta-galactosidase, Acid beta-galactosidase, Lactase, Elastin receptor 1, GLB1, ELNR1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)
  • Antonicelli, F., et al. Wound Repair Regen 17(5):631-638(2009)
  • Hofer, D., et al. Hum. Mutat. 30(8):1214-1221(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This GLB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-109 amino acids from the N-terminal region of human GLB1.
NCBI Gene ID #:
2720
NCBI Official Name:
Beta-galactosidase
NCBI Official Symbol:
GLB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
76 kDa
Protein Accession #:
P16278
Protein GI Number:
215273939
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P16278
User NOte:
Optimal dilutions for each application to be determined by the researcher.