ALG8 Antibody
| Code | Size | Price |
|---|
| PSI-59-956-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase, Asparagine-linked glycosylation protein 8 homolog, Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase, Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase, ALG8
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the ALG6/ALG8
glucosyltransferase family. The encoded protein catalyzes the
addition of the second glucose residue to the lipid-linked
oligosaccharide precursor for N-linked glycosylation of proteins.
Mutations in this gene have been associated with congenital
disorder of glycosylation type Ih (CDG-Ih). Alternatively spliced
transcript variants encoding different isoforms have been
identified.
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Stolting, T., et al. Mol. Genet. Metab. 98(3):305-309(2009)
- Jaeken, J., et al. Curr. Opin. Pediatr. 16(4):434-439(2004)
- Schollen, E., et al. J. Med. Genet. 41(7):550-556(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This ALG8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-41 amino acids from the N-terminal region of human ALG8.
NCBI Gene ID #:
79053
NCBI Official Name:
Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
NCBI Official Symbol:
ALG8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
Q9BVK2
Protein GI Number:
143811361
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9BVK2
User NOte:
Optimal dilutions for each application to be determined by the researcher.