MOCS1 Antibody

ProSci
Product Code: PSI-60-344
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-344-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in CEM cell line lysates (35ug/lane).

Western blot analysis in CEM cell line lysates (35ug/lane).

Further Information

Additional Names:
Molybdenum cofactor biosynthesis protein 1, Cell migration-inducing gene 11 protein, Molybdenum cofactor synthesis-step 1 protein A-B, Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein A, Cyclic pyranopterin monophosphate synthase accessory protein, Molybdenum cofactor biosynthesis protein C, MOCS1
Application Note:
For WB starting dilution is: 1:1000
Background:
Molybdenum cofactor biosynthesis is a conserved pathway leading to the biological activation of molybdenum. The protein encoded by this gene is involved in this pathway. This gene was originally thought to produce a bicistronic mRNA with the potential to produce two proteins (MOCS1A and MOCS1B) from adjacent open reading frames. However, only the first open reading frame (MOCS1A) has been found to encode a protein from the putative bicistronic mRNA, whereas additional splice variants, whose full-length natures have yet to be determined, are likely to produce a fusion between the two open reading frames. This gene is defective in patients with molybdenum cofactor deficiency, type A. A related pseudogene has been identified on chromosome 16.
Background References:
  • Sass, J.O., et al. Brain Dev. (2009) In press :
  • Arenas, M., et al. J. Inherit. Metab. Dis. 32(4):560-569(2009)
  • Ichida, K., et al. Nucleosides Nucleotides Nucleic Acids 25 (9-11), 1087-1091 (2006) :
  • Macaya, A., et al. Neuropediatrics 36(6):389-394(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MOCS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-58 amino acids from the N-terminal region of human MOCS1.
NCBI Gene ID #:
4337
NCBI Official Name:
Molybdenum cofactor biosynthesis protein 1
NCBI Official Symbol:
MOCS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
70 kDa
Protein Accession #:
Q9NZB8
Protein GI Number:
30913216
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9NZB8
User NOte:
Optimal dilutions for each application to be determined by the researcher.