HM13 Antibody
| Code | Size | Price |
|---|
| PSI-57-702-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Minor histocompatibility antigen H13, 3423-, Intramembrane protease 1, IMP-1, IMPAS-1, hIMP1, Presenilin-like protein 3, Signal peptide peptidase, HM13, H13, IMP1, PSL3, SPP
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene, which localizes to the
endoplasmic reticulum, catalyzes intramembrane proteolysis of some
signal peptides after they have been cleaved from a preprotein.
This activity is required to generate signal sequence-derived human
lymphocyte antigen-E epitopes that are recognized by the immune
system, and to process hepatitis C virus core protein. The encoded
protein is an integral membrane protein with sequence motifs
characteristic of the presenilin-type aspartic proteases. Multiple
transcript variants encoding several different isoforms have been
found for this gene.
Background References:
- Sato, T., et al. Biochemistry 45(28):8649-8656(2006)
- Loureiro, J., et al. Nature 441(7095):894-897(2006)
- Urny, J., et al. Biochim. Biophys. Acta 1759 (3-4), 159-165 (2006) :
- Friedmann, E., et al. J. Biol. Chem. 279(49):50790-50798(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HM13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-354 amino acids from the C-terminal region of human HM13.
NCBI Gene ID #:
81502
NCBI Official Name:
Minor histocompatibility antigen H13
NCBI Official Symbol:
HM13
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
Q8TCT9
Protein GI Number:
25008563
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q8TCT9
User NOte:
Optimal dilutions for each application to be determined by the researcher.