MTHFR Antibody
| Code | Size | Price |
|---|
| PSI-60-733-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Methylenetetrahydrofolate reductase, MTHFR
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene catalyzes the conversion
of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a
co-substrate for homocysteine remethylation to methionine. Genetic
variation in this gene influences susceptibility to occlusive
vascular disease, neural tube defects, colon cancer and acute
leukemia, and mutations in this gene are associated with
methylenetetrahydrofolate reductase deficiency.
Background References:
- Singh, K., et al.Postgrad Med 56(4):267-269(2010)
- Harisha, P.N., et al.Neurosurg Pediatr 6(4):364-367(2010)
- Wu, H.C., et al. Anticancer Res. 30(9):3573-3577(2010)
- Magnowski, P., et al. Ginekol. Pol. 81(7):506-510(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse
Immunogen:
This MTHFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-292 amino acids from the Central region of human MTHFR.
NCBI Gene ID #:
4524
NCBI Official Name:
Methylenetetrahydrofolate reductase
NCBI Official Symbol:
MTHFR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
75 kDa
Protein Accession #:
P42898
Protein GI Number:
56405339
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P42898
User NOte:
Optimal dilutions for each application to be determined by the researcher.