CTNS Antibody
| Code | Size | Price |
|---|
| PSI-60-528-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cystinosin, CTNS
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a seven-transmembrane domain protein
that functions to transport cystine out of lysosomes. Its activity
is driven by the H+ electrochemical gradient of the lysosomal
membrane. Mutations in this gene cause cystinosis, a lysosomal
storage disorder. Alternative splicing results in multiple
transcript variants.
Background References:
- Taranta, A., et al. Pediatr. Nephrol. 25(7):1263-1267(2010)
- Bellomo, F., et al. Free Radic. Biol. Med. 48(7):865-872(2010)
- Kumar, A., et al. J. Biosci. 35(1):21-25(2010)
- Aldahmesh, M.A., et al. Ophthalmic Genet. 30(4):185-189(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CTNS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-367 amino acids from the C-terminal region of human CTNS.
NCBI Gene ID #:
1497
NCBI Official Name:
Cystinosin
NCBI Official Symbol:
CTNS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
O60931
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
O60931
User NOte:
Optimal dilutions for each application to be determined by the researcher.