MAN1A2 Antibody

ProSci
Product Code: PSI-61-241
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-241-200ul200ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:2000 dilution Lane 1: A431 whole cell lysate Lane 2: U-2OS whole cell lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:2000 dilution Lane 1: A431 whole cell lysate Lane 2: U-2OS whole cell lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB, 3.2.1.113, Mannosidase alpha class 1A member 2, Processing alpha-1,2-mannosidase IB, Alpha-1,2-mannosidase IB, MAN1A2, MAN1B
Application Note:
For WB starting dilution is: 1:2000
Background:
Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
Background References:
  • Tremblay L.O.,et al.Glycobiology 8:585-595(1998).
  • Gregory S.G.,et al.Nature 441:315-321(2006).
  • Bienvenut W.V.,et al.Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
  • Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MAN1A2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 342-373 amino acids from the Central region of human MAN1A2.
NCBI Gene ID #:
10905
NCBI Official Name:
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB
NCBI Official Symbol:
MAN1A2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
73 kDa
Protein Accession #:
O60476
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
O60476
User NOte:
Optimal dilutions for each application to be determined by the researcher.