NAA10 Antibody
| Code | Size | Price |
|---|
| PSI-61-219-200ul | 200ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
N-alpha-acetyltransferase 10, 2.3.1.-, 2.3.1.88, N-terminal acetyltransferase complex ARD1 subunit homolog A, NatA catalytic subunit Naa10, NAA10, ARD1, ARD1A, TE2
Application Note:
For WB starting dilution is: 1:2000
Background:
Catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. The NAT activity may be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration. Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development.
Background References:
- Tribioli C.,et al.Hum. Mol. Genet. 3:1061-1068(1994).
- Arnesen T.,et al.Biochem. J. 386:433-443(2005).
- Ross M.T.,et al.Nature 434:325-337(2005).
- Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This NAA10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 135-167 amino acids from the Central region of human NAA10.
NCBI Gene ID #:
8260
NCBI Official Name:
N-alpha-acetyltransferase 10
NCBI Official Symbol:
NAA10
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa
Protein Accession #:
P41227
Protein GI Number:
728880
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P41227
User NOte:
Optimal dilutions for each application to be determined by the researcher.