FXN Antibody
| Code | Size | Price |
|---|
| PSI-60-803-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Frataxin, mitochondrial, Friedreich ataxia protein, Fxn, Frataxin intermediate form, i-FXN, Frataxin(56-210), m56-FXN, Frataxin(78-210), d-FXN, m78-FXN, Frataxin mature form, Frataxin(81-210), m81-FXN, FXN, FRDA, X25
Application Note:
For WB starting dilution is: 1:1000
Background:
This nuclear gene encodes a mitochondrial protein which
belongs to FRATAXIN family. The protein functions in regulating
mitochondrial iron transport and respiration. The expansion of
intronic trinucleotide repeat GAA results in Friedreich ataxia.
Alternative splicing results in multiple transcript variants.
Background References:
- Tsai, C.L., et al. Biochemistry 49(43):9132-9139(2010)
- Thierbach, R., et al. Biochem. J. 432(1):165-172(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Marino, T.C., et al. Clin. Genet. 77(6):598-600(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human FXN.
NCBI Gene ID #:
2395
NCBI Official Name:
Frataxin, mitochondrial
NCBI Official Symbol:
FXN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
Q16595
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q16595
User NOte:
Optimal dilutions for each application to be determined by the researcher.