PLA2G3 Antibody

ProSci
Product Code: PSI-60-172
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-60-172-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Uterus tissue lysates (35ug/lane).

Western blot analysis in Uterus tissue lysates (35ug/lane).

Further Information

Additional Names:
Group 3 secretory phospholipase A2, Group III secretory phospholipase A2, GIII sPLA2, sPLA2-III, Phosphatidylcholine 2-acylhydrolase 3, PLA2G3
Application Note:
For WB starting dilution is: 1:1000
Background:
PLA2G3 belongs to the family of secreted phospholipase A2 (sPLA2; EC 3.1.1.4) proteins. These Ca(2+)-dependent lipolytic enzymes have a conserved Ca(2+)-binding loop and a his-asp dyad in the catalytic site (Murakami et al., 2003 [PubMed 12522102]).
Background References:
  • Wang, G., et al. J. Neurochem. 114(4):1039-1048(2010) Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010) Segat, L., et al. Vaccine 28(10):2201-2206(2010) Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010) Sato, H., et al. Biochem. J. 421(1):17-27(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PLA2G3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 446-474 amino acids from the C-terminal region of human PLA2G3.
NCBI Gene ID #:
50487
NCBI Official Name:
Group 3 secretory phospholipase A2
NCBI Official Symbol:
PLA2G3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
Protein Accession #:
Q9NZ20
Protein GI Number:
317373314
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9NZ20
User NOte:
Optimal dilutions for each application to be determined by the researcher.