ACSL3 Antibody
| Code | Size | Price |
|---|
| PSI-58-620-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Long-chain-fatty-acid--CoA ligase 3, Long-chain acyl-CoA synthetase 3, LACS 3, ACSL3, ACS3, FACL3, LACS3
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is an isozyme of the
long-chain fatty-acid-coenzyme A ligase family. Although differing
in substrate specificity, subcellular localization, and tissue
distribution, all isozymes of this family convert free long-chain
fatty acids into fatty acyl-CoA esters, and thereby play a key role
in lipid biosynthesis and fatty acid degradation. This isozyme is
highly expressed in brain, and preferentially utilizes myristate,
arachidonate, and eicosapentaenoate as substrates. The amino acid
sequence of this isozyme is 92% identical to that of rat homolog.
Two transcript variants encoding the same protein have been found
for this gene.
Background References:
- Weedon-Fekjaer, M.S., et al. J. Lipid Res. 51(7):1886-1896(2010)
- Cao, A., et al. J. Biol. Chem. 285(22):16664-16674(2010)
- Perera, F., et al. PLoS ONE(2), E4488 (2009) :
- Yao, H., et al. J. Biol. Chem. 283(2):849-854(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This ACSL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 528-556 amino acids from the C-terminal region of human ACSL3.
NCBI Gene ID #:
2181
NCBI Official Name:
Long-chain-fatty-acid--CoA ligase 3
NCBI Official Symbol:
ACSL3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
80 kDa
Protein Accession #:
O95573
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
O95573
User NOte:
Optimal dilutions for each application to be determined by the researcher.