TGM3 Antibody
| Code | Size | Price |
|---|
| PSI-59-272-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Protein-glutamine gamma-glutamyltransferase E, Transglutaminase E, TG(E), TGE, TGase E, Transglutaminase-3, TGase-3, Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain, Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain, TGM3
Application Note:
For WB starting dilution is: 1:1000
Background:
Transglutaminases are enzymes that catalyze the
crosslinking of proteins by epsilon-gamma glutamyl lysine
isopeptide bonds. While the primary structure of transglutaminases
is not conserved, they all have the same amino acid sequence at
their active sites and their activity is calcium-dependent. The
protein encoded by this gene consists of two polypeptide chains
activated from a single precursor protein by proteolysis. The
encoded protein is involved the later stages of cell envelope
formation in the epidermis and hair follicle.
Background References:
- Yamane, A., et al. FEBS J. 277(17):3564-3574(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Negishi, A., et al. Cancer Sci. 100(9):1605-1611(2009)
- Fujimoto, A., et al. J. Hum. Genet. 54(8):461-465(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TGM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 539-567 amino acids from the C-terminal region of human TGM3.
NCBI Gene ID #:
7053
NCBI Official Name:
Protein-glutamine gamma-glutamyltransferase E
NCBI Official Symbol:
TGM3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
77 kDa
Protein Accession #:
Q08188
Protein GI Number:
257051080
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q08188
User NOte:
Optimal dilutions for each application to be determined by the researcher.