CBR3 Antibody

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ProSci
Product Code: PSI-56-713
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-56-713-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of CBR3 using rabbit polyclonal CBR3 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CBR3 gene.
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Flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Western blot analysis of CBR3 using rabbit polyclonal CBR3 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CBR3 gene.
Flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Documents

Further Information

Additional Names:
Carbonyl reductase [NADPH] 3, NADPH-dependent carbonyl reductase 3, CBR3
Application Note:
For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50
Background:
Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.
Background References:
  • Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)
  • Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009)
  • Zhang, J., et al. Pharm. Res. 26(9):2209-2215(2009)
  • Choi, J.Y., et al. Clin. Cancer Res. 15(16):5258-5266(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CBR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-224 amino acids from the C-terminal region of human CBR3.
NCBI Gene ID #:
874
NCBI Official Name:
Carbonyl reductase [NADPH] 3
NCBI Official Symbol:
CBR3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
31 kDa
Protein Accession #:
O75828
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Obesity,Signal Transduction
Swissprot #:
O75828
User NOte:
Optimal dilutions for each application to be determined by the researcher.