MAN2A1 Antibody
| Code | Size | Price |
|---|
| PSI-55-532-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Alpha-mannosidase 2, Golgi alpha-mannosidase II, AMan II, Man II, Mannosidase alpha class 2A member 1, Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, MAN2A1, MANA2
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
This gene encodes a protein which is a member of family 38
of the glycosyl hydrolases. The protein is located in the Golgi and
catalyzes the final hydrolytic step in the asparagine-linked
oligosaccharide (N-glycan) maturation pathway. Mutations in the
mouse homolog of this gene have been shown to cause a systemic
autoimmune disease similar to human systemic lupus erythematosus.
Background References:
- Han, S., et al. Leuk. Res. 34(10):1271-1274(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Zhou, J.B., et al. Med. Sci. Monit. 16 (6), BR179-BR183 (2010) :
- Miyagawa, H., et al. Rheumatology (Oxford) 47(2):158-164(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MAN2A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 456-482 amino acids from the Central region of human MAN2A1.
NCBI Gene ID #:
4124
NCBI Official Name:
Alpha-mannosidase 2
NCBI Official Symbol:
MAN2A1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
131 kDa
Protein Accession #:
Q16706
Protein GI Number:
146345453
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q16706
User NOte:
Optimal dilutions for each application to be determined by the researcher.