AASS Antibody
Code | Size | Price |
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PSI-55-621-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Alpha-aminoadipic semialdehyde synthase, mitochondrial, LKR/SDH, Lysine ketoglutarate reductase, LKR, LOR, Saccharopine dehydrogenase, SDH, AASS
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
This gene encodes a bifunctional enzyme that catalyzes the
first two steps in the mammalian lysine degradation pathway. The
N-terminal and the C-terminal portions of this enzyme contain
lysine-ketoglutarate reductase and saccharopine dehydrogenase
activity, respectively, resulting in the conversion of lysine to
alpha-aminoadipic semialdehyde. Mutations in this gene are
associated with familial hyperlysinemia.
Background References:
- Sacksteder, K.A., et al. Am. J. Hum. Genet. 66(6):1736-1743(2000)
- Papes, F., et al. Biochem. J. 344 PT 2, 555-563 (1999) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This AASS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 805-834 amino acids from the C-terminal region of human AASS.
NCBI Gene ID #:
10157
NCBI Official Name:
Alpha-aminoadipic semialdehyde synthase, mitochondrial
NCBI Official Symbol:
AASS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
102 kDa
Protein Accession #:
Q9UDR5
Protein GI Number:
46396032
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9UDR5
User NOte:
Optimal dilutions for each application to be determined by the researcher.