GCDH Antibody
| Code | Size | Price |
|---|
| PSI-56-724-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Glutaryl-CoA dehydrogenase, mitochondrial, GCD, GCDH
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene belongs to the acyl-CoA
dehydrogenase family. It catalyzes the oxidative decarboxylation of
glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway
of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses
electron transfer flavoprotein as its electron acceptor. The enzyme
exists in the mitochondrial matrix as a homotetramer of 45-kD
subunits. Alternatively spliced transcript variants encoding
different isoforms have been identified.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Park, J.D., et al. J. Korean Med. Sci. 25(6):957-960(2010)
- Strauss, K.A., et al. Brain 133 (PT 1), 76-92 (2010) :
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey
Immunogen:
This GCDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human GCDH.
NCBI Gene ID #:
2639
NCBI Official Name:
Glutaryl-CoA dehydrogenase, mitochondrial
NCBI Official Symbol:
GCDH
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
Q92947
Protein GI Number:
2492631
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q92947
User NOte:
Optimal dilutions for each application to be determined by the researcher.