PTPLA Antibody
| Code | Size | Price |
|---|
| PSI-57-074-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1, 3-hydroxyacyl-CoA dehydratase 1, HACD1, Cementum attachment protein, Protein-tyrosine phosphatase-like member A, PTPLA, HACD1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene contains a characteristic
catalytic motif of the protein tyrosine phosphatases (PTPs) family.
The PTP motif of this protein has the highly conserved arginine
residue replaced by a proline residue; thus it may represent a
distinct class of PTPs. Members of the PTP family are known to be
signaling molecules that regulate a variety of cellular processes.
This gene was preferentially expressed in both adult and fetal
heart. A much lower expression level was detected in skeletal and
smooth muscle tissues, and no expression was observed in other
tissues. The tissue specific expression in the developing and adult
heart suggests a role in regulating cardiac development and
differentiation.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Liang, X., et al. Hum. Mutat. 30(3):463-471(2009)
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PTPLA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human PTPLA.
NCBI Gene ID #:
9200
NCBI Official Name:
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1
NCBI Official Symbol:
PTPLA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
B0YJ81
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
B0YJ81
User NOte:
Optimal dilutions for each application to be determined by the researcher.