ACSS2 Antibody
| Code | Size | Price |
|---|
| PSI-56-934-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Acetyl-coenzyme A synthetase, cytoplasmic, Acetate--CoA ligase, Acetyl-CoA synthetase, ACS, AceCS, Acyl-CoA synthetase short-chain family member 2, Acyl-activating enzyme, ACSS2, ACAS2
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a cytosolic enzyme that catalyzes the
activation of acetate for use in lipid synthesis and energy
generation. The protein acts as a monomer and produces acetyl-CoA
from acetate in a reaction that requires ATP. Expression of this
gene is regulated by sterol regulatory element-binding proteins,
transcription factors that activate genes required for the
synthesis of cholesterol and unsaturated fatty acids. Alternative
splicing results in multiple transcript variants. [provided by
RefSeq].
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Yilmaz, S., et al. Genomics 96(1):57-65(2010)
- Ban, H.J., et al. BMC Genet. 11, 26 (2010) :
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ACSS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-290 amino acids from the Central region of human ACSS2.
NCBI Gene ID #:
55902
NCBI Official Name:
Acetyl-coenzyme A synthetase, cytoplasmic
NCBI Official Symbol:
ACSS2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
79 kDa
Protein Accession #:
Q9NR19
Protein GI Number:
20137525
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9NR19
User NOte:
Optimal dilutions for each application to be determined by the researcher.