CYP2C18 Antibody

ProSci
Product Code: PSI-63-614
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-614-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of CYP2C18 Antibody in HL-60 cell line lysates (35ug/lane)
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Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with CYP2C18 Antibody ,which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Western blot analysis of CYP2C18 Antibody in HL-60 cell line lysates (35ug/lane)
Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with CYP2C18 Antibody ,which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Further Information

Additional Names:
Cytochrome P450 2C18, CYPIIC18, Cytochrome P450-6b/29c, CYP2C18
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
CYP2C18 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined.
Background References:
  • Beausoleil,S.A., et.al., Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004)
  • Nelson,D.R., et.al., Pharmacogenetics 14 (1), 1-18 (2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CYP2C18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 448-478 amino acids from the C-terminal region of human CYP2C18.
NCBI Gene ID #:
1562
NCBI Official Name:
Cytochrome P450 2C18
NCBI Official Symbol:
CYP2C18
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
P33260
Protein GI Number:
67476954
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Obesity,Signal Transduction
Swissprot #:
P33260
User NOte:
Optimal dilutions for each application to be determined by the researcher.