NDUAB Antibody
Code | Size | Price |
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PSI-55-237-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11, Complex I-B147, CI-B147, NADH-ubiquinone oxidoreductase subunit B147, NDUFA11
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
NDUFA11 encodes a subunit of the membrane-bound
mitochondrial complex I. Complex I is composed of numerous subunits
and functions as the NADH-ubiquinol reductase of the mitochondrial
electron transport chain. Mutations in this gene are associated
with severe mitochondrial complex I deficiency. Alternate splicing
results in multiple transcript variants.
Background References:
- Berger, I., et al. Ann. Neurol. 63(3):405-408(2008)
- Takagaki, K., et al. Biochem. Biophys. Res. Commun. 309(2):351-358(2003)
- Murray, J., et al. J. Biol. Chem. 278(16):13619-13622(2003)
- Carroll, J., et al. J. Biol. Chem. 277(52):50311-50317(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NDUAB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the Central region of human NDUAB.
NCBI Gene ID #:
126328
NCBI Official Name:
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
NCBI Official Symbol:
NDUFA11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
15 kDa
Protein Accession #:
Q86Y39
Protein GI Number:
52000823
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q86Y39
User NOte:
Optimal dilutions for each application to be determined by the researcher.