BCAT1 Antibody
| Code | Size | Price |
|---|
| PSI-55-059-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Branched-chain-amino-acid aminotransferase, cytosolic, BCAT(c), Protein ECA39, BCAT1, BCT1, ECA39
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes the cytosolic form of the enzyme
branched-chain amino acid transaminase. This enzyme catalyzes the
reversible transamination of branched-chain alpha-keto acids to
branched-chain L-amino acids essential for cell growth. Two
different clinical disorders have been attributed to a defect of
branched-chain amino acid transamination: hypervalinemia and
hyperleucine-isoleucinemia. As there is also a gene encoding a
mitochondrial form of this enzyme, mutations in either gene may
contribute to these disorders. Alternatively spliced transcript
variants have been described.
Background References:
- Eijgelsheim, M., et al. Hum. Mol. Genet. 19(19):3885-3894(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Barber, M.J., et al. PLoS ONE(3), E9763 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This BCAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-107 amino acids from the Central region of human BCAT1.
NCBI Gene ID #:
586
NCBI Official Name:
Branched-chain-amino-acid aminotransferase, cytosolic
NCBI Official Symbol:
BCAT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
P54687
Protein GI Number:
215274162
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P54687
User NOte:
Optimal dilutions for each application to be determined by the researcher.