UROC1 Antibody
| Code | Size | Price |
|---|
| PSI-55-667-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase, UROC1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes an enzyme involved in histidine
catabolism, metabolizing urocanic acid to formiminoglutamic acid.
The gene product is known to protect the skin from ultra violet
rays and is contained in human sweat. Deficiency of this gene
product in the liver is an apparent cause of mental retardation.
Multiple transcript variants encoding different isoforms have been
found for this gene.
Background References:
- Espinos, C., et al. J. Med. Genet. 46(6):407-411(2009)
- Yamada, S., et al. Oncogene 23(35):5901-5911(2004)
- Retey, J. Arch. Biochem. Biophys. 314(1):1-16(1994)
- Kalafatic, Z., et al. Metab. Clin. Exp. 29(11):1013-1019(1980)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This UROC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-430 amino acids from the Central region of human UROC1.
NCBI Gene ID #:
131669
NCBI Official Name:
Urocanate hydratase
NCBI Official Symbol:
UROC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
75 kDa
Protein Accession #:
Q96N76
Protein GI Number:
22256789
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q96N76
User NOte:
Optimal dilutions for each application to be determined by the researcher.