POFUT2 Antibody
Code | Size | Price |
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PSI-56-696-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
GDP-fucose protein O-fucosyltransferase 2, Peptide-O-fucosyltransferase 2, O-FucT-2, POFUT2, C21orf80, FUT13, KIAA0958
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
Fucose is typically found as a terminal modification of
branched chain glycoconjugates, but it also exists in direct
O-linkage to serine or threonine residues within cystine knot
motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or
thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an
O-fucosyltransferase that use THBS type-1 repeats as substrates
(Luo et al., 2006 [PubMed 16464857]).
Background References:
- Feng, T., et al. Hum. Genet. 128(3):269-280(2010)
- Luo, Y., et al. J. Biol. Chem. 281(14):9385-9392(2006)
- Luo, Y., et al. J. Biol. Chem. 281(14):9393-9399(2006)
- Menzel, O., et al. Genomics 84(2):320-330(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This POFUT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the Central region of human POFUT2.
NCBI Gene ID #:
23275
NCBI Official Name:
GDP-fucose protein O-fucosyltransferase 2
NCBI Official Symbol:
POFUT2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
Q9Y2G5
Protein GI Number:
59803123
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9Y2G5
User NOte:
Optimal dilutions for each application to be determined by the researcher.