ATP1B3 Antibody
| Code | Size | Price |
|---|
| PSI-56-621-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Sodium/potassium-transporting ATPase subunit beta-3, Sodium/potassium-dependent ATPase subunit beta-3, ATPB-3, CD298, ATP1B3
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene belongs to the family of
Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily
of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein
responsible for establishing and maintaining the electrochemical
gradients of Na and K ions across the plasma membrane. These
gradients are essential for osmoregulation, for sodium-coupled
transport of a variety of organic and inorganic molecules, and for
electrical excitability of nerve and muscle. This enzyme is
composed of two subunits, a large catalytic subunit (alpha) and a
smaller glycoprotein subunit (beta). The beta subunit regulates,
through assembly of alpha/beta heterodimers, the number of sodium
pumps transported to the plasma membrane. The glycoprotein subunit
of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a
beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene
exists for this gene, and it is located on chromosome 2. [provided
by RefSeq].
Background References:
- Floyd, R.V., et al. Reprod Sci 17(4):366-376(2010)
- Aughey, R.J., et al. J. Appl. Physiol. 103(1):39-47(2007)
- Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
- Chiampanichayakul, S., et al. Tissue Antigens 68(6):509-517(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ATP1B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-270 amino acids from the C-terminal region of human ATP1B3.
NCBI Gene ID #:
483
NCBI Official Name:
Sodium/potassium-transporting ATPase subunit beta-3
NCBI Official Symbol:
ATP1B3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
P54709
Protein GI Number:
1703470
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P54709
User NOte:
Optimal dilutions for each application to be determined by the researcher.