CYB5A Antibody
| Code | Size | Price |
|---|
| PSI-57-429-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cytochrome b5, Microsomal cytochrome b5 type A, MCB5, CYB5A, CYB5
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene is a membrane-bound
cytochrome that reduces ferric hemoglobin (methemoglobin) to
ferrous hemoglobin, which is required for stearyl-CoA-desaturase
activity. Defects in this gene are a cause of type IV hereditary
methemoglobinemia. Three transcript variants encoding different
isoforms have been found for this gene.
Background References:
- Gardner, A.M., et al. J. Biol. Chem. 285(31):23850-23857(2010)
- Kok, R.C., et al. J. Clin. Endocrinol. Metab. 95(3):994-999(2010)
- Sacco, J.C., et al. Pharmacogenet. Genomics 20(1):26-37(2010)
- Maghzal, G.J., et al. J. Biol. Chem. 283(18):12014-12025(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CYB5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the Central region of human CYB5A.
NCBI Gene ID #:
1528
NCBI Official Name:
Cytochrome b5
NCBI Official Symbol:
CYB5A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
15 kDa
Protein Accession #:
P00167
Protein GI Number:
117809
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P00167
User NOte:
Optimal dilutions for each application to be determined by the researcher.