DHRS2 Antibody

ProSci
Product Code: PSI-61-889
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-889-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:16000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 ug per lane.
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DHRS2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western Blot at 1:16000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 ug per lane.
DHRS2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Dehydrogenase/reductase SDR family member 2, mitochondrial, 111-, Dicarbonyl reductase HEP27, Protein D, DHRS2
Application Note:
For WB starting dilution is: 1:16000

For IHC-P starting dilution is: 1:50~100
Background:
DHRS2 displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. DHRS2 do not reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. This protein may inhibit cell replication.
Background References:
  • Monge, M., et al. Carcinogenesis 30(8):1288-1297(2009)
  • Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009)
  • Shafqat, N., et al. Cell. Mol. Life Sci. 63(10):1205-1213(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DHRS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-225 amino acids from the C-terminal region of human DHRS2.
NCBI Gene ID #:
10202
NCBI Official Name:
Dehydrogenase/reductase SDR family member 2, mitochondrial
NCBI Official Symbol:
DHRS2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
30 kDa
Protein Accession #:
Q13268
Protein GI Number:
527504085
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q13268
User NOte:
Optimal dilutions for each application to be determined by the researcher.