SLC22A1 Antibody
| Code | Size | Price |
|---|
| PSI-57-369-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Solute carrier family 22 member 1, Organic cation transporter 1, hOCT1, SLC22A1, OCT1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
Polyspecific organic cation transporters in the liver,
kidney, intestine, and other organs are critical for elimination of
many endogenous small organic cations as well as a wide array of
drugs and environmental toxins. This gene is one of three similar
cation transporter genes located in a cluster on chromosome 6. The
encoded protein contains twelve putative transmembrane domains and
is a plasma integral membrane protein. Two transcript variants
encoding two different isoforms have been found for this gene, but
only the longer variant encodes a functional transporter. [provided
by RefSeq].
Background References:
- Takahashi, N., et al. J. Hum. Genet. 55(11):731-737(2010)
- Jablonski, K.A., et al. Diabetes 59(10):2672-2681(2010)
- Hu, M., et al. Pharmacogenet. Genomics 20(10):634-637(2010)
- Gambineri, A., et al. J. Clin. Endocrinol. Metab. 95 (10), E204-E208 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SLC22A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 511-539 amino acids from the C-terminal region of human SLC22A1.
NCBI Gene ID #:
6580
NCBI Official Name:
Solute carrier family 22 member 1
NCBI Official Symbol:
SLC22A1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
61 kDa
Protein Accession #:
O15245
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
O15245
User NOte:
Optimal dilutions for each application to be determined by the researcher.