MOSC2 Antibody

ProSci
Product Code: PSI-63-589
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-589-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of MOSC2 Antibody in Hela cell line lysates (35ug/lane)
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Formalin-fixed and paraffin-embedded human lung carcinoma reacted with MOSC2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
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Western blot analysis of MOSC2 using rabbit polyclonal MOSC2 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MOSC2 gene.

Western blot analysis of MOSC2 Antibody in Hela cell line lysates (35ug/lane)
Formalin-fixed and paraffin-embedded human lung carcinoma reacted with MOSC2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Western blot analysis of MOSC2 using rabbit polyclonal MOSC2 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MOSC2 gene.

Further Information

Additional Names:
Mitochondrial amidoxime reducing component 2, mARC2, 1---, Molybdenum cofactor sulfurase C-terminal domain-containing protein 2, MOSC domain-containing protein 2, Moco sulfurase C-terminal domain-containing protein 2, MARC2, MOSC2
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50
Background:
Catalytic component of the benzamidoxime prodrug-converting complex, a complex required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. Benzamidoxime is an amidine prodrug produced by N-hydroxylation which is used to enhance bioavailability and increase intestinal absorption. It is then reduced into benzamidine, its active amidine, by the benzamidoxime prodrug-converting complex.
Background References:
  • Havemeyer,A., et.al., J. Biol. Chem. 281 (46), 34796-34802 (2006)
  • Simpson,J.C., et.al.,EMBO Rep.(3), 287-292 (2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MOSC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-300 amino acids from the C-terminal region of human MOSC2.
NCBI Gene ID #:
54996
NCBI Official Name:
Mitochondrial amidoxime reducing component 2
NCBI Official Symbol:
Mar-02
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
Q969Z3
Protein GI Number:
74760692
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q969Z3
User NOte:
Optimal dilutions for each application to be determined by the researcher.