ACOT11 Antibody
| Code | Size | Price |
|---|
| PSI-55-048-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Acyl-coenzyme A thioesterase 11, Acyl-CoA thioesterase 11, 312-, Acyl-CoA thioester hydrolase 11, Adipose-associated thioesterase, Brown fat-inducible thioesterase, BFIT, ACOT11, BFIT, KIAA0707, THEA
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Background:
This gene encodes a member of the acyl-CoA thioesterase
family which catalyse the conversion of activated fatty acids to
the corresponding non-esterified fatty acid and coenzyme A.
Expression of a mouse homolog in brown adipose tissue is induced by
low temperatures and repressed by warm temperatures. Higher levels
of expression of the mouse homolog has been found in
obesity-resistant mice compared with obesity-prone mice, suggesting
a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing
results in transcript variants.
Background References:
- Kirkby, B., et al. Prog. Lipid Res. 49(4):366-377(2010)
- Hunt, M.C., et al. J. Lipid Res. 46(9):2029-2032(2005)
- Adams, S.H., et al. Biochem. J. 360 (PT 1), 135-142 (2001) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ACOT11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-575 amino acids from the C-terminal region of human ACOT11.
NCBI Gene ID #:
26027
NCBI Official Name:
Acyl-coenzyme A thioesterase 11
NCBI Official Symbol:
ACOT11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
Q8WXI4
Protein GI Number:
21363000
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q8WXI4
User NOte:
Optimal dilutions for each application to be determined by the researcher.