CYP2A13 Antibody

ProSci
Product Code: PSI-63-568
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-568-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of CYP2A13 Antibody in MDA-MB231 cell line lysates (35ug/lane)
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Formalin-fixed and paraffin-embedded human breast carcinoma reacted with CYP2A13 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
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Western blot analysis of CYP2A13 Antibody in MDA-MB231 cell line lysates (35ug/lane)
Formalin-fixed and paraffin-embedded human breast carcinoma reacted with CYP2A13 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Further Information

Additional Names:
Cytochrome P450 2A13, CYPIIA13, CYP2A13
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50
Background:
CYP2A13 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been determined, it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a major nitrosamine specific to tobacco.
Background References:
  • Smith,G., et.al., Xenobiotica 28 (12), 1129-1165 (1998)
  • Nelson,D.R., et.al., Pharmacogenetics 14 (1), 1-18 (2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CYP2A13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 446-477 amino acids from the C-terminal region of human CYP2A13.
NCBI Gene ID #:
1553
NCBI Official Name:
Cytochrome P450 2A13
NCBI Official Symbol:
CYP2A13
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
Protein Accession #:
Q16696
Protein GI Number:
77416854
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q16696
User NOte:
Optimal dilutions for each application to be determined by the researcher.