GIF Antibody
| Code | Size | Price |
|---|
| PSI-56-771-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Gastric intrinsic factor, Intrinsic factor, IF, INF, GIF, IFMH
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
This gene is a member of the cobalamin transport protein
family. It encodes a glycoprotein secreted by parietal cells of the
gastric mucosa and is required for adequate absorption of vitamin
B12. Vitamin B12 is necessary for erythrocyte maturation and
mutations in this gene may lead to congenital pernicious anemia.
Background References:
- Levine, A.J., et al. Cancer Epidemiol. Biomarkers Prev. 19(7):1812-1821(2010)
- Andersen, C.B., et al. Nature 464(7287):445-448(2010)
- Ament, A.E., et al. Br. J. Haematol. 144(4):622-624(2009)
- Remacha, A.F., et al. Ann. Hematol. 87(7):599-600(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GIF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-218 amino acids from the Central region of human GIF.
NCBI Gene ID #:
2694
NCBI Official Name:
Gastric intrinsic factor
NCBI Official Symbol:
GIF
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
P27352
Protein GI Number:
62906845
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P27352
User NOte:
Optimal dilutions for each application to be determined by the researcher.