EDG2 Antibody
| Code | Size | Price |
|---|
| PSI-62-138-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Lysophosphatidic acid receptor 1, LPA receptor 1, LPA-1, Lysophosphatidic acid receptor Edg-2, LPAR1, EDG2, LPA1
Application Note:
For WB starting dilution is: 1:1000
Background:
The EDG2 integral membrane protein is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion.
Background References:
- Matsuda, A., et al., Oncogene 22(21):3307-3318 (2003).
- Van Leeuwen, F.N., et al., J. Biol. Chem. 278(1):400-406 (2003).
- Shida, D., et al., Cancer Res. 63(7):1706-1711 (2003).
- Cervera, P., et al., Glia 38(2):126-136 (2002).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This EDG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human EDG2.
NCBI Gene ID #:
1902
NCBI Official Name:
Lysophosphatidic acid receptor 1
NCBI Official Symbol:
LPAR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
Q92633
Protein GI Number:
26454626
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Obesity,Signal Transduction,Growth Factor
Swissprot #:
Q92633
User NOte:
Optimal dilutions for each application to be determined by the researcher.