MYLK3 Antibody
| Code | Size | Price |
|---|
| PSI-56-077-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Myosin light chain kinase 3, Cardiac-MyBP-C-associated Ca/CaM kinase, Cardiac-MLCK, MYLK3, MLCK
Application Note:
For WB starting dilution is: 1:1000
Background:
Phosphorylation of cardiac myosin heavy chains (see MYH7B,
MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase,
such as MYLK3, potentiates the force and rate of cross-bridge
recruitment in cardiac myocytes (Chan et al., 2008 [PubMed
18202317]).
Background References:
- Al-Sadi, R., et al. J. Immunol. 180(8):5653-5661(2008)
- Chan, J.Y., et al. Circ. Res. 102(5):571-580(2008)
- Seguchi, O., et al. J. Clin. Invest. 117(10):2812-2824(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MYLK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 535-562 amino acids from the Central region of human MYLK3.
NCBI Gene ID #:
91807
NCBI Official Name:
Myosin light chain kinase 3
NCBI Official Symbol:
MYLK3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
88 kDa
Protein Accession #:
Q32MK0
Protein GI Number:
254763411
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q32MK0
User NOte:
Optimal dilutions for each application to be determined by the researcher.