FERMT2 Antibody
| Code | Size | Price |
|---|
| PSI-60-238-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Fermitin family homolog 2, Kindlin-2, Mitogen-inducible gene 2 protein, MIG-2, Pleckstrin homology domain-containing family C member 1, PH domain-containing family C member 1, FERMT2, KIND2, MIG2, PLEKHC1
Application Note:
For WB starting dilution is: 1:1000
Background:
FERMT2 participates in the connection between ECM adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites.
Background References:
- An, Z., et al. Int. J. Cancer 127(9):1999-2008(2010) Bledzka, K., et al. J. Biol. Chem. 285(40):30370-30374(2010) Lai-Cheong, J.E., et al. Int. J. Biochem. Cell Biol. 42(5):595-603(2010) Lai-Cheong, J.E., et al. J. Invest. Dermatol. 128(9):2156-2165(2008) Ma, Y.Q., et al. J. Cell Biol. 181(3):439-446(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse
Immunogen:
This FERMT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 641-669 amino acids from the C-terminal region of human FERMT2.
NCBI Gene ID #:
10979
NCBI Official Name:
Fermitin family homolog 2
NCBI Official Symbol:
FERMT2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
78 kDa
Protein Accession #:
Q96AC1
Protein GI Number:
38258220
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q96AC1
User NOte:
Optimal dilutions for each application to be determined by the researcher.