CIB1 Antibody

ProSci
Product Code: PSI-60-813
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-813-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

Further Information

Additional Names:
Calcium and integrin-binding protein 1, CIB, Calcium- and integrin-binding protein, CIBP, Calmyrin, DNA-PKcs-interacting protein, Kinase-interacting protein, KIP, SNK-interacting protein 2-28, SIP2-28, CIB1, CIB, KIP, PRKDCIP
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. This protein also interacts with integrin alpha(IIb)beta(3), which may implicate this protein as a regulatory molecule for alpha(IIb)beta(3).
Background References:
  • Bailey, S.D., et al. Diabetes Care (2010) In press :
  • Jarman, K.E., et al. J. Biol. Chem. 285(1):483-492(2010)
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
  • Yamniuk, A.P., et al. Protein Sci. 18(5):1128-1134(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This CIB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-151 amino acids from the C-terminal region of human CIB1.
NCBI Gene ID #:
10519
NCBI Official Name:
Calcium and integrin-binding protein 1
NCBI Official Symbol:
CIB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
Q99828
Protein GI Number:
134047806
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q99828
User NOte:
Optimal dilutions for each application to be determined by the researcher.