PIGO Antibody

ProSci
Product Code: PSI-59-078
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-078-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Y79 cell line lysates (35ug/lane).

Western blot analysis in Y79 cell line lysates (35ug/lane).

Further Information

Additional Names:
GPI ethanolamine phosphate transferase 3, 2---, Phosphatidylinositol-glycan biosynthesis class O protein, PIG-O, PIGO
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least two alternatively spliced transcripts encoding distinct isoforms have been found for this gene.
Background References:
  • Bailey, S.D., et al. Diabetes Care (2010) In press :
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
  • Humphray, S.J., et al. Nature 429(6990):369-374(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PIGO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 955-983 amino acids from the C-terminal region of human PIGO.
NCBI Gene ID #:
84720
NCBI Official Name:
GPI ethanolamine phosphate transferase 3
NCBI Official Symbol:
PIGO
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
119 kDa
Protein Accession #:
Q8TEQ8
Protein GI Number:
61252289
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8TEQ8
User NOte:
Optimal dilutions for each application to be determined by the researcher.