MYOT Antibody
| Code | Size | Price |
|---|
| PSI-59-047-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Myotilin, 57 kDa cytoskeletal protein, Myofibrillar titin-like Ig domains protein, Titin immunoglobulin domain protein, MYOT, TTID
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a cystoskeletal protein which plays a
significant role in the stability of thin filaments during muscle
contraction. This protein binds F-actin, crosslinks actin
filaments, and prevents latrunculin A-induced filament disassembly.
Mutations in this gene have been associated with limb-girdle
muscular dystrophy and myofibrillar myopathies. Several
alternatively spliced transcript variants of this gene have been
described, but the full-length nature of some of these variants has
not been determined.
Background References:
- Bailey, S.D., et al. Diabetes Care (2010) In press :
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Shalaby, S., et al. J. Neuropathol. Exp. Neurol. 68(6):701-707(2009)
- Heikkinen, O., et al. J. Biomol. NMR 44(2):107-112(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MYOT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-155 amino acids from the Central region of human MYOT.
NCBI Gene ID #:
9499
NCBI Official Name:
Myotilin
NCBI Official Symbol:
MYOT
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
Q9UBF9
Protein GI Number:
311033402
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9UBF9
User NOte:
Optimal dilutions for each application to be determined by the researcher.