ARHGEF5 Antibody

ProSci
Product Code: PSI-58-689
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-689-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A2058 cell line lysates (35ug/lane).

Western blot analysis in A2058 cell line lysates (35ug/lane).

Further Information

Additional Names:
Rho guanine nucleotide exchange factor 5, Ephexin-3, Guanine nucleotide regulatory protein TIM, Oncogene TIM, Transforming immortalized mammary oncogene, p60 TIM, ARHGEF5, TIM
Application Note:
For WB starting dilution is: 1:1000
Background:
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.
Background References:
  • Bailey, S.D., et al. Diabetes Care (2010) In press :
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
  • Wang, Z., et al. J. Biol. Chem. 284(42):28599-28606(2009)
  • Lin, Y.M., et al. Mol. Carcinog. 47(12):925-933(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ARHGEF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1503-1530 amino acids from the C-terminal region of human ARHGEF5.
NCBI Gene ID #:
7984
NCBI Official Name:
Rho guanine nucleotide exchange factor 5
NCBI Official Symbol:
ARHGEF5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
177 kDa
Protein Accession #:
Q12774
Protein GI Number:
290457679
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q12774
User NOte:
Optimal dilutions for each application to be determined by the researcher.