TRPC1 Antibody

ProSci
Product Code: PSI-58-767
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-767-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 2
Western Blot at 1:1000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 ug per lane.
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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Western Blot at 1:1000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 ug per lane.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Further Information

Additional Names:
Short transient receptor potential channel 1, TrpC1, Transient receptor protein 1, TRP-1, TRPC1, TRP1
Application Note:
For WB starting dilution is: 1:1000
Background:
TRPC1 belongs to the transient receptor potential (TRP) superfamily of cation channels. TRP cation channels are involved in diverse physiologic processes, including receptor- and store-operated Ca(2+) entry, mineral absorption, and cell death. They also function as sensors for pain, heat, cold, sound, stretch, and osmotic changes (Zhang et al., 2009 [PubMed 19193631]).
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Bomben, V.C., et al. Glia 58(10):1145-1156(2010)
  • Lu, M., et al. J. Mol. Endocrinol. 44(5):285-294(2010)
  • Gonzalez-Cobos, J.C., et al. Front. Biosci. 15, 1023-1039 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rabbit
Immunogen:
This TRPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 765-793 amino acids from the C-terminal region of human TRPC1.
NCBI Gene ID #:
7220
NCBI Official Name:
Short transient receptor potential channel 1
NCBI Official Symbol:
TRPC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
91 kDa
Protein Accession #:
P48995
Protein GI Number:
1351302
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P48995
User NOte:
Optimal dilutions for each application to be determined by the researcher.