ARHGEF1 Antibody
| Code | Size | Price |
|---|
| PSI-58-055-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Rho guanine nucleotide exchange factor 1, 115 kDa guanine nucleotide exchange factor, p115-RhoGEF, p115RhoGEF, Sub15, ARHGEF1
Application Note:
For WB starting dilution is: 1:1000
Background:
Rho GTPases play a fundamental role in numerous cellular
processes that are initiated by extracellular stimuli that work
through G protein coupled receptors. The encoded protein may form
complex with G proteins and stimulate Rho-dependent signals.
Multiple alternatively spliced transcript variants have been found
for this gene, but the full-length nature of some variants has not
been defined.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Loirand, G., et al. Med Sci (Paris) 26 (6-7), 561-563 (2010) :
- Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ARHGEF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-192 amino acids from the N-terminal region of human ARHGEF1.
NCBI Gene ID #:
9138
NCBI Official Name:
Rho guanine nucleotide exchange factor 1
NCBI Official Symbol:
ARHGEF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
102 kDa
Protein Accession #:
Q92888
Protein GI Number:
34395524
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q92888
User NOte:
Optimal dilutions for each application to be determined by the researcher.