TPM2 Antibody

ProSci
Product Code: PSI-59-276
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-276-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Further Information

Additional Names:
Tropomyosin beta chain, Beta-tropomyosin, Tropomyosin-2, TPM2, TMSB
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Martins-de-Souza, D., et al.Psychiatr Res 44(14):989-991(2010)
  • Assinder, S.J., et al. Mol. Carcinog. 49(6):525-531(2010)
  • Ochala, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107(21):9807-9812(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Rabbit, Rat
Immunogen:
This TPM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-280 amino acids from the C-terminal region of human TPM2.
NCBI Gene ID #:
7169
NCBI Official Name:
Tropomyosin beta chain
NCBI Official Symbol:
TPM2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
P07951
Protein GI Number:
136090
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P07951
User NOte:
Optimal dilutions for each application to be determined by the researcher.