SKAP2 Antibody

ProSci
Product Code: PSI-59-191
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-191-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 1
Western blot analysis in U937 cell line lysates (35ug/lane).

Western blot analysis in U937 cell line lysates (35ug/lane).

Further Information

Additional Names:
Src kinase-associated phosphoprotein 2, Pyk2/RAFTK-associated protein, Retinoic acid-induced protein 70, SKAP55 homolog, SKAP-55HOM, SKAP-HOM, Src family-associated phosphoprotein 2, Src kinase-associated phosphoprotein 55-related protein, Src-associated adapter protein with PH and SH3 domains, SKAP2, PRAP, RA70, SAPS, SCAP2, SKAP55R
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to the src family kinases. This protein is similar to the src kinase associated phosphoprotein 1. It is an adaptor protein that is thought to play an essential role in the src signaling pathway in various cells. It inhibits PTK2B/RAFTK activity and regulates alpha-synuclein phosphorylation.
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Qu, H.Q., et al. Hum. Mol. Genet. 19(12):2534-2538(2010)
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
  • Barrett, J.C., et al. Nat. Genet. 41(6):703-707(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This SKAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-165 amino acids from the Central region of human SKAP2.
NCBI Gene ID #:
8935
NCBI Official Name:
Src kinase-associated phosphoprotein 2
NCBI Official Symbol:
SKAP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
O75563
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O75563
User NOte:
Optimal dilutions for each application to be determined by the researcher.