TEC Antibody
| Code | Size | Price |
|---|
| PSI-58-456-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Tyrosine-protein kinase Tec, TEC, PSCTK4
Application Note:
For WB starting dilution is: 1:1000
Background:
TEC belongs to the Tec family
of non-receptor protein-tyrosine kinases containing a pleckstrin
homology domain. Tec family kinases are involved in the
intracellular signaling mechanisms of cytokine receptors,
lymphocyte surface antigens, heterotrimeric G-protein coupled
receptors, and integrin molecules. They are also key players in the
regulation of the immune functions. Tec kinase is an integral
component of T cell signaling and has a distinct role in T cell
activation. This gene may be associated with myelodysplastic
syndrome.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Ebert, A.D., et al. Traffic 11(6):813-826(2010)
- Susaki, K., et al. Immunol. Lett. 127(2):135-142(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TEC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human TEC.
NCBI Gene ID #:
7006
NCBI Official Name:
Tyrosine-protein kinase Tec
NCBI Official Symbol:
TEC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
74 kDa
Protein Accession #:
P42680
Protein GI Number:
158518392
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P42680
User NOte:
Optimal dilutions for each application to be determined by the researcher.