ProSci

RRN3 Antibody

Product Code:
 
PSI-59-102
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in HepG2 cell line lysates (35ug/lane).
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Western blot analysis in HepG2 cell line lysates (35ug/lane).

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PSI-59-102-400ul400ul£626.00
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Further Information

Additional Names:
RNA polymerase I-specific transcription initiation factor RRN3, Transcription initiation factor IA, TIF-IA, RRN3, TIFIA
Application Note:
For WB starting dilution is: 1:1000
Background:
Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC). Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction (By similarity).
Background References:
  • Bierhoff, H., et al. Mol. Cell. Biol. 28(16):4988-4998(2008)
  • Amit, M., et al. BMC Mol. Biol. 8, 109 (2007) :
  • Mayer, C., et al. Genes Dev. 18(4):423-434(2004)
  • Hirschler-Laszkiewicz, I., et al. J. Biol. Chem. 278(21):18953-18959(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RRN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-305 amino acids from the Central region of human RRN3.
NCBI Gene ID #:
54700
NCBI Official Name:
RNA polymerase I-specific transcription initiation factor RRN3
NCBI Official Symbol:
RRN3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
74 kDa
Protein Accession #:
Q9NYV6
Protein GI Number:
74719591
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9NYV6
User NOte:
Optimal dilutions for each application to be determined by the researcher.