ITK Antibody
| Code | Size | Price |
|---|
| PSI-63-163-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Tyrosine-protein kinase ITK/TSK, Interleukin-2-inducible T-cell kinase, IL-2-inducible T-cell kinase, Kinase EMT, T-cell-specific kinase, Tyrosine-protein kinase Lyk, ITK, EMT, LYK
Application Note:
For WB starting dilution is: 1:1000
Background:
ITK is an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.
Background References:
- Brazin, K.N., et al., Proc. Natl. Acad. Sci. U.S.A. 99(4):1899-1904 (2002).
- Hawkins, J., et al., Protein Expr. Purif. 22(2):211-219 (2001).
- Janis, E.M., et al., Genomics 23(1):269-271 (1994).
- Gibson, S., et al., Blood 82(5):1561-1572 (1993).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ITK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-198 amino acids from the Central region of human ITK.
NCBI Gene ID #:
3702
NCBI Official Name:
Tyrosine-protein kinase ITK/TSK
NCBI Official Symbol:
ITK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
72 kDa
Protein Accession #:
Q08881
Protein GI Number:
585361
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
Q08881
User NOte:
Optimal dilutions for each application to be determined by the researcher.