SIT1 Antibody
| Code | Size | Price |
|---|
| PSI-58-721-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Signaling threshold-regulating transmembrane adapter 1, SHP2-interacting transmembrane adapter protein, Suppression-inducing transmembrane adapter 1, gp30/40, SIT1, SIT
Application Note:
For WB starting dilution is: 1:1000
Background:
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells.
Background References:
- Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009)
- Tedoldi, S., et al. Blood 107(1):213-221(2006)
- Tao, W.A., et al. Nat. Methods 2(8):591-598(2005)
- Tao, W.A., et al. Nat. Methods 2(8):591-598(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This SIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the C-terminal region of human SIT1.
NCBI Gene ID #:
27240
NCBI Official Name:
Signaling threshold-regulating transmembrane adapter 1
NCBI Official Symbol:
SIT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa
Protein Accession #:
Q9Y3P8
Protein GI Number:
74753488
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9Y3P8
User NOte:
Optimal dilutions for each application to be determined by the researcher.