ZCCHC12 Antibody

ProSci
Product Code: PSI-59-405
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-405-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A549 cell line lysates (35ug/lane).

Western blot analysis in A549 cell line lysates (35ug/lane).

Further Information

Additional Names:
Zinc finger CCHC domain-containing protein 12, Smad-interacting zinc finger protein 1, ZCCHC12, SIZN1
Application Note:
For WB starting dilution is: 1:1000
Background:
Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression (By similarity).
Background References:
  • Cho, G., et al. J. Biol. Chem. 284(29):19592-19600(2009)
  • Li, H., et al. Acta Biochim. Biophys. Sin. (Shanghai) 41(7):535-544(2009)
  • Cho, G., et al. Am. J. Med. Genet.146A (20), 2644-2650 (2008) :
  • Cho, G., et al. Mol. Cell. Biol. 28(5):1565-1572(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ZCCHC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the C-terminal region of human ZCCHC12.
NCBI Gene ID #:
170261
NCBI Official Name:
Zinc finger CCHC domain-containing protein 12
NCBI Official Symbol:
ZCCHC12
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
Q6PEW1
Protein GI Number:
85718626
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q6PEW1
User NOte:
Optimal dilutions for each application to be determined by the researcher.