B4GALT4 Antibody
| Code | Size | Price |
|---|
| PSI-59-958-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Beta-1,4-galactosyltransferase 4, Beta-1,4-GalTase 4, Beta4Gal-T4, b4Gal-T4, 241-, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4, N-acetyllactosamine synthase, Nal synthase, Lactotriaosylceramide beta-1,4-galactosyltransferase, Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase, B4GALT4
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is one of seven beta-1,4-galactosyltransferase
(beta4GalT) genes. They encode type II membrane-bound glycoproteins
that appear to have exclusive specificity for the donor substrate
UDP-galactose; all transfer galactose in a beta1,4 linkage to
similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a
distinct function in the biosynthesis of different glycoconjugates
and saccharide structures. As type II membrane proteins, they have
an N-terminal hydrophobic signal sequence that directs the protein
to the Golgi apparatus and which then remains uncleaved to function
as a transmembrane anchor. By sequence similarity, the beta4GalTs
form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and
beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme
encoded by this gene appears to mainly play a role in glycolipid
biosynthesis. Two alternatively spliced transcript variants have
been found for this gene.
Background References:
- Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
- Guo, S., et al. Glycobiology 11(10):813-820(2001)
- Suzuki, Y., et al. Genome Res. 11(5):677-684(2001)
- Amado, M., et al. Biochim. Biophys. Acta 1473(1):35-53(1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This B4GALT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-117 amino acids from the Central region of human B4GALT4.
NCBI Gene ID #:
8702
NCBI Official Name:
Beta-1,4-galactosyltransferase 4
NCBI Official Symbol:
B4GALT4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa
Protein Accession #:
O60513
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O60513
User NOte:
Optimal dilutions for each application to be determined by the researcher.