PPP1R16B Antibody
Code | Size | Price |
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PSI-59-308-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Protein phosphatase 1 regulatory inhibitor subunit 16B, Ankyrin repeat domain-containing protein 4, CAAX box protein TIMAP, TGF-beta-inhibited membrane-associated protein, hTIMAP, PPP1R16B, ANKRD4, KIAA0823
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is membrane-associated
and contains five ankyrin repeats, a protein
phosphatase-1-interacting domain, and a carboxy-terminal CAAX box
domain. Synthesis of the encoded protein is inhibited by
transforming growth factor beta-1. The protein may bind to the
membrane through its CAAX box domain and may act as a signaling
molecule through interaction with protein phosphatase-1.
Alternatively spliced transcript variants encoding different
isoforms have been identified in this gene.
Background References:
- Csortos, C., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 295 (3), L440-L450 (2008) :
- Kim, K., et al. Biochem. Biophys. Res. Commun. 338(3):1327-1334(2005)
- Homma, K., et al. J. Mol. Biol. 343(5):1207-1220(2004)
- Cao, W., et al. Am. J. Physiol., Cell Physiol. 283 (1), C327-C337 (2002) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This PPP1R16B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 372-399 amino acids from the Central region of human PPP1R16B.
NCBI Gene ID #:
26051
NCBI Official Name:
Protein phosphatase 1 regulatory inhibitor subunit 16B
NCBI Official Symbol:
PPP1R16B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
64 kDa
Protein Accession #:
Q96T49
Protein GI Number:
22256977
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q96T49
User NOte:
Optimal dilutions for each application to be determined by the researcher.