RELT Antibody

ProSci
Product Code: PSI-59-313
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-313-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in T47D cell line lysates (35ug/lane).

Western blot analysis in T47D cell line lysates (35ug/lane).

Further Information

Additional Names:
Tumor necrosis factor receptor superfamily member 19L, Receptor expressed in lymphoid tissues, RELT, TNFRSF19L
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.
Background References:
  • Cusick, J.K., et al. Cell. Immunol. 261(1):1-8(2010)
  • Polek, T.C., et al. Biochem. Biophys. Res. Commun. 349(3):1016-1024(2006)
  • Bossen, C., et al. J. Biol. Chem. 281(20):13964-13971(2006)
  • Cusick, J.K., et al. Biochem. Biophys. Res. Commun. 340(2):535-543(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RELT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-413 amino acids from the C-terminal region of human RELT.
NCBI Gene ID #:
84957
NCBI Official Name:
Tumor necrosis factor receptor superfamily member 19L
NCBI Official Symbol:
RELT
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
Protein Accession #:
Q969Z4
Protein GI Number:
21264092
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q969Z4
User NOte:
Optimal dilutions for each application to be determined by the researcher.